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Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers

HIV-1 envelope glycoproteins (Env) and Env-based immunogens usually do not interact efficiently with the inferred germline precursors of known broadly neutralizing antibodies (bNAbs). This deficiency may be one reason why Env and Env-based immunogens are not efficient at inducing bNAbs. We evaluated...

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書誌詳細
出版年:Virology
主要な著者: Sliepen, Kwinten, Medina-Ramírez, Max, Yasmeen, Anila, Moore, John P., Klasse, Per Johan, Sanders, Rogier W.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712445/
https://ncbi.nlm.nih.gov/pubmed/26433050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.002
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