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HIV-1 envelope trimer design and immunization strategies to induce broadly neutralizing antibodies
The identification of multiple broadly neutralizing antibodies (bNAb) against the HIV-1 envelope glycoprotein (Env) trimer has facilitated its structural characterization and guided Env immunogen design. High-resolution structures of a soluble, native-like trimer (BG505 SOSIP.664) enabled the detail...
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| Vydáno v: | Trends Immunol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454186/ https://ncbi.nlm.nih.gov/pubmed/26869204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2016.01.007 |
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