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UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

Plasmodium salivary sporozoites are the infectious form of the malaria parasite and are dormant inside salivary glands of Anopheles mosquitoes. During dormancy, protein translation is inhibited by the kinase UIS1 that phosphorylates serine 59 in the eukaryotic initiation factor 2α (eIF2α). De-phosph...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Zhang, Min, Mishra, Satish, Sakthivel, Ramanavelan, Fontoura, Beatriz M. A., Nussenzweig, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712141/
https://ncbi.nlm.nih.gov/pubmed/26735921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005370
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