Conserved Protective Mechanisms in Radiation and Genetically Attenuated uis3(-) and uis4(-) Plasmodium Sporozoites

Immunization with radiation attenuated Plasmodium sporozoites (RAS) elicits sterile protective immunity against sporozoite challenge in murine models and in humans. Similarly to RAS, the genetically attenuated sporozoites (GAPs) named uis3(-), uis4(-) and P36p(-) have arrested growth during the live...

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Detalhes bibliográficos
Main Authors: Kumar, Kota Arun, Baxter, Peter, Tarun, Alice S., Kappe, Stefan H. I., Nussenzweig, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637429/
https://ncbi.nlm.nih.gov/pubmed/19214236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004480
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