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Class II-Restricted Protective Immunity Induced by Malaria Sporozoites

The irradiated-sporozoite vaccine elicits sterile immunity against Plasmodium parasites in experimental rodent hosts and human volunteers. Based on rodent malaria models, it has been proposed that CD8(+) T cells are the key protective effector mechanism required in sporozoite-induced immunity. To in...

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Detalhes bibliográficos
Main Authors: Oliveira, Giane A., Kumar, Kota Arun, Calvo-Calle, J. Mauricio, Othoro, Caroline, Altszuler, David, Nussenzweig, Victor, Nardin, Elizabeth H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258813/
https://ncbi.nlm.nih.gov/pubmed/18160479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00566-07
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