A Linear Peptide Containing Minimal T- and B-Cell Epitopes of Plasmodium falciparum Circumsporozoite Protein Elicits Protection against Transgenic Sporozoite Challenge

An effective malaria vaccine is needed to address the public health tragedy resulting from the high levels of morbidity and mortality caused by Plasmodium parasites. The first protective immune mechanism identified in the irradiated sporozoite vaccine, the “gold standard” for malaria preerythrocytic...

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Autors principals: Calvo-Calle, J. Mauricio, Oliveira, Giane A., Watta, Carol Othoro, Soverow, Jonathan, Parra-Lopez, Carlos, Nardin, Elizabeth H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698101/
https://ncbi.nlm.nih.gov/pubmed/17030584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01151-06
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