Phase I Trial of an Alhydrogel Adjuvanted Hepatitis B Core Virus-Like Particle Containing Epitopes of Plasmodium falciparum Circumsporozoite Protein

The objectives of this non-randomized, non-blinded, dose-escalating Phase I clinical trial were to assess the safety, reactogenicity and immunogenicity of ICC-1132 formulated with Alhydrogel (aluminum hydroxide) in 51 healthy, malaria-naive adults aged 18 to 45 years. ICC-1132 (Malariavax) is a reco...

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Detalhes bibliográficos
Main Authors: Gregson, Aric L., Oliveira, Giane, Othoro, Caroline, Calvo-Calle, J. Mauricio, Thorton, George B., Nardin, Elizabeth, Edelman, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216688/
https://ncbi.nlm.nih.gov/pubmed/18253503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001556
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