PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

In response to environmental stresses, the mammalian serine threonine kinases PERK, GCN2, HRI, and PKR phosphorylate the regulatory serine 51 of the eukaryotic translation initiation factor 2α (eIF2α) to inhibit global protein synthesis. Plasmodium, the protozoan that causes malaria, expresses three...

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Detalhes bibliográficos
Main Authors: Zhang, Min, Mishra, Satish, Sakthivel, Ramanavelan, Rojas, Margarito, Ranjan, Ravikant, Sullivan, William J., Fontoura, Beatriz M. A., Ménard, Robert, Dever, Thomas E., Nussenzweig, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309761/
https://ncbi.nlm.nih.gov/pubmed/22355110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121567109
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