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Inhibition of LtxA Toxicity by Blocking Cholesterol Binding With Peptides

The leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans kills host immune cells, allowing the bacterium to establish an ecological niche in the upper aerodigestive tract of its human host. The interaction of LtxA with human immune cells is both complex and multifaceted, involving mem...

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Publicado en:Mol Oral Microbiol
Autores principales: Brown, Angela C., Koufos, Evan, Balashova, Nataliya, Boesze-Battaglia, Kathleen, Lally, Edward T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712104/
https://ncbi.nlm.nih.gov/pubmed/26352738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12133
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