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Aggregatibacter actinomycetemcomitans leukotoxin induces cytosol acidification in LFA-1 expressing immune cells
Studies have suggested that Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) kills human LFA-1(CD11a/CD18)-bearing immune cells through a lysosomal-mediated mechanism. Lysosomes are membrane-bound cellular organelles that contain an array of acid hydrolases that are capable of breaking down b...
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| Publicado no: | Mol Oral Microbiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712095/ https://ncbi.nlm.nih.gov/pubmed/26361372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12136 |
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