Aggregatibacter actinomycetemcomitans LtxA Hijacks Endocytic Trafficking Pathways in Human Lymphocytes

Leukotoxin (LtxA), from oral pathogen Aggregatibacter actinomycetemcomitans, is a secreted membrane-damaging protein. LtxA is internalized by β2 integrin LFA-1 (CD11a/CD18)-expressing leukocytes and ultimately causes cell death; however, toxin localization in the host cell is poorly understood and t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pathogens
Egile Nagusiak: Lally, Edward T, Boesze-Battaglia, Kathleen, Dhingra, Anuradha, Gomez, Nestor M, Lora, Jinery, Mitchell, Claire H, Giannakakis, Alexander, Fahim, Syed A, Benz, Roland, Balashova, Nataliya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168647/
https://ncbi.nlm.nih.gov/pubmed/31973183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9020074
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