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Use of a Cholesterol Recognition Amino Acid Consensus Peptide To Inhibit Binding of a Bacterial Toxin to Cholesterol

Recognition of and binding to cholesterol on the host cell membrane is an initial step in the mechanism of numerous pathogens, including viruses, bacteria, and bacterial toxins; however, a viable method of inhibiting this interaction has not yet been uncovered. Here, we describe the mechanism by whi...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Koufos, Evan, Chang, En Hyung, Rasti, Elnaz S., Krueger, Eric, Brown, Angela C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945288/
https://ncbi.nlm.nih.gov/pubmed/27504950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00430
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