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Inhibition of APOBEC3G Activity Impedes Double-Strand DNA Repair
The cellular cytidine deaminase APOBEC3G (A3G) was first described as an anti-HIV-1 restriction factor by directly deaminating reverse transcripts of the viral genome. HIV-1 Vif neutralizes the activity of A3G, primarily by mediating degradation of A3G to establish effective infection in host target...
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| Publicado en: | FEBS J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712096/ https://ncbi.nlm.nih.gov/pubmed/26460502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13556 |
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