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Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif
In the absence of HIV-1 Vif protein, the host antiviral deaminase APOBEC3G (A3G) restricts the production of infectious HIV-1 by deamination of dC residues in the negative ssDNA produced by reverse transcription. The Vif protein averts the lethal threat of deamination by precluding the packaging of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139112/ https://ncbi.nlm.nih.gov/pubmed/21763507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.058 |
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