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Inhibition of APOBEC3G Activity Impedes Double-Strand DNA Repair
The cellular cytidine deaminase APOBEC3G (A3G) was first described as an anti-HIV-1 restriction factor by directly deaminating reverse transcripts of the viral genome. HIV-1 Vif neutralizes the activity of A3G, primarily by mediating degradation of A3G to establish effective infection in host target...
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| Publié dans: | FEBS J |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712096/ https://ncbi.nlm.nih.gov/pubmed/26460502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13556 |
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