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Holliday junctions generate super-bright antibodies and antibody fragments in sortase-catalyzed reactions
Site-specific modification of proteins with fluorophores can render a protein fluorescent without compromising its function. To avoid self-quenching of multiple fluorophores installed in close proximity, we used Holliday junctions to label proteins site-specifically. Holliday junctions enable modifi...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711269/ https://ncbi.nlm.nih.gov/pubmed/26252716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201505277 |
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