IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation

BACKGROUND: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known about how these extracellular factors instruct innate immune cell epigenomes to engage specific differentiation states. Human monocytes diff...

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Библиографические подробности
Опубликовано в: :Genome Biol
Главные авторы: Vento-Tormo, Roser, Company, Carlos, Rodríguez-Ubreva, Javier, de la Rica, Lorenzo, Urquiza, José M., Javierre, Biola M., Sabarinathan, Radhakrishnan, Luque, Ana, Esteller, Manel, Aran, Josep M., Álvarez-Errico, Damiana, Ballestar, Esteban
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711003/
https://ncbi.nlm.nih.gov/pubmed/26758199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0863-2
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