تحميل...
Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics
BACKGROUND: Carcinogenic hexavalent chromium [Cr(VI)] requires cellular reduction to generate DNA damage. Metabolism of Cr(VI) by its principal reducer ascorbate (Asc) lacks a Cr(V) intermediate, which is abundant in reactions with a minor reducing agent, glutathione. Cultured cells are widely used...
محفوظ في:
| الحاوية / القاعدة: | Environ Health Perspect |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Institute of Environmental Health Sciences
2015
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710604/ https://ncbi.nlm.nih.gov/pubmed/25977998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1409434 |
| الوسوم: |
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