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Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

Immunoglobulin G (IgG) antibodies that trap viruses in cervicovaginal mucus (CVM) via adhesive interactions between IgG-Fc and mucins have recently emerged as a promising strategy to block vaginally transmitted infections. The array of IgG bound to a virus particle appears to trap the virus by makin...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Wessler, Timothy, Chen, Alex, McKinley, Scott A., Cone, Richard, Forest, Gregory, Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707974/
https://ncbi.nlm.nih.gov/pubmed/26771004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00108
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