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Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus

To reliably infect a primate model for human immunodeficiency virus (HIV), ∼10,000-fold more virus must be delivered vaginally than intravenously. However, the vaginal mechanisms that help protect against HIV are poorly understood. Here, we report that human cervicovaginal mucus (CVM), obtained from...

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Detalhes bibliográficos
Main Authors: Lai, Samuel K., Hida, Kaoru, Shukair, Shetha, Wang, Ying-Ying, Figueiredo, Anna, Cone, Richard, Hope, Thomas J., Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772788/
https://ncbi.nlm.nih.gov/pubmed/19692470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01899-08
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