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Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

Eliciting broadly neutralizing antibodies (bnAb) in cervicovaginal mucus (CVM) represents a promising “first line of defense” strategy to reduce vaginal HIV transmission. However, it remains unclear what levels of bnAb must be present in CVM to effectively reduce infection. We approached this comple...

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Detalhes bibliográficos
Main Authors: McKinley, Scott A., Chen, Alex, Shi, Feng, Wang, Simi, Mucha, Peter J., Forest, M. Gregory, Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072659/
https://ncbi.nlm.nih.gov/pubmed/24967706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100598
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