Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

Given the difficulty in finding a cure for HIV/AIDS, a promising prevention strategy to reduce HIV transmission is to directly block infection at the portal of entry. The recent Thai RV144 trial offered the first evidence that an antibody-based vaccine may block heterosexual HIV transmission. Unfort...

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Detalhes bibliográficos
Main Authors: Chen, Alex, McKinley, Scott A., Wang, Simi, Shi, Feng, Mucha, Peter J., Forest, M. Gregory, Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Systems Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017286/
https://ncbi.nlm.nih.gov/pubmed/24806935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.038
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