Carregant...

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

Here, we show that the synaptic vesicle protein SV2A is the brain binding site of levetiracetam (LEV), a new antiepileptic drug with a unique activity profile in animal models of seizure and epilepsy. The LEV-binding site is enriched in synaptic vesicles, and photoaffinity labeling of purified synap...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lynch, Berkley A., Lambeng, Nathalie, Nocka, Karl, Kensel-Hammes, Patricia, Bajjalieh, Sandra M., Matagne, Alain, Fuks, Bruno
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC470764/
https://ncbi.nlm.nih.gov/pubmed/15210974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308208101
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!