Large Structural Change in Isolated Synaptic Vesicles upon Loading with Neurotransmitter

The size of a synaptic vesicle (SV) is generally thought to be determined by the amount of lipid and membrane protein it contains. Once formed, it is thought to remain constant in size. Using fluorescence correlation spectroscopy and cryogenic electron microscopy, we show that glutamatergic vesicles...

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Detalhes bibliográficos
Main Authors: Budzinski, Kristi L., Allen, Richard W., Fujimoto, Bryant S., Kensel-Hammes, P., Belnap, David M., Bajjalieh, Sandra M., Chiu, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770603/
https://ncbi.nlm.nih.gov/pubmed/19883601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.032
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