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Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin

The Gram-negative pathogen Vibrio cholerae causes diarrheal disease through the export of enterotoxins. The V. cholerae RTX toxin was previously identified and characterized by its ability to round human laryngeal epithelial (HEp-2) cells. Further investigation determined that cell rounding is cause...

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Détails bibliographiques
Auteurs principaux: Sheahan, Kerri-Lynn, Cordero, Christina L., Fullner Satchell, Karla J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC470754/
https://ncbi.nlm.nih.gov/pubmed/15199181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401104101
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