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Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin

The Gram-negative pathogen Vibrio cholerae causes diarrheal disease through the export of enterotoxins. The V. cholerae RTX toxin was previously identified and characterized by its ability to round human laryngeal epithelial (HEp-2) cells. Further investigation determined that cell rounding is cause...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sheahan, Kerri-Lynn, Cordero, Christina L., Fullner Satchell, Karla J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470754/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401104101
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