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Autoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domain

Vibrio cholerae RTX is a large multifunctional bacterial toxin that causes actin crosslinking. Due to its size, it was predicted to undergo proteolytic cleavage during translocation into host cells to deliver activity domains to the cytosol. In this study, we identified a domain within the RTX toxin...

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Détails bibliographiques
Auteurs principaux: Sheahan, Kerri-Lynn, Cordero, Christina L, Satchell, Karla J Fullner
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868911/
https://ncbi.nlm.nih.gov/pubmed/17464284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601700
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