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Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin

The Gram-negative pathogen Vibrio cholerae causes diarrheal disease through the export of enterotoxins. The V. cholerae RTX toxin was previously identified and characterized by its ability to round human laryngeal epithelial (HEp-2) cells. Further investigation determined that cell rounding is cause...

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Autores principales: Sheahan, Kerri-Lynn, Cordero, Christina L., Fullner Satchell, Karla J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC470754/
https://ncbi.nlm.nih.gov/pubmed/15199181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401104101
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