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The Actin Cross-Linking Domain of the Vibrio cholerae RTX Toxin Directly Catalyzes the Covalent Cross-Linking of Actin

Vibrio cholerae is a Gram-negative bacterial pathogen that exports enterotoxins to alter host cells and elicit diarrheal disease. Among the secreted toxins is the multifunctional RTX toxin, which causes cell rounding and actin depolymerization by covalently cross-linking actin monomers into dimers,...

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Detalhes bibliográficos
Main Authors: Cordero, Christina L., Kudryashov, Dmitry S., Reisler, Emil, Fullner Satchell, Karla J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2255562/
https://ncbi.nlm.nih.gov/pubmed/16954226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605275200
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