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Cells release prions in association with exosomes

Prion diseases are infectious neurodegenerative disorders linked to the accumulation in the central nervous system of the abnormally folded prion protein (PrP) scrapie (PrPsc), which is thought to be the infectious agent. Once present, PrPsc catalyzes the conversion of naturally occurring cellular P...

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Bibliographische Detailangaben
Hauptverfasser: Fevrier, Benoit, Vilette, Didier, Archer, Fabienne, Loew, Damarys, Faigle, Wolfgang, Vidal, Michel, Laude, Hubert, Raposo, Graça
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470735/
https://ncbi.nlm.nih.gov/pubmed/15210972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308413101
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