Cells release prions in association with exosomes

Prion diseases are infectious neurodegenerative disorders linked to the accumulation in the central nervous system of the abnormally folded prion protein (PrP) scrapie (PrPsc), which is thought to be the infectious agent. Once present, PrPsc catalyzes the conversion of naturally occurring cellular P...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Fevrier, Benoit, Vilette, Didier, Archer, Fabienne, Loew, Damarys, Faigle, Wolfgang, Vidal, Michel, Laude, Hubert, Raposo, Graça
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15210972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308413101
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