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Cells release prions in association with exosomes

Prion diseases are infectious neurodegenerative disorders linked to the accumulation in the central nervous system of the abnormally folded prion protein (PrP) scrapie (PrPsc), which is thought to be the infectious agent. Once present, PrPsc catalyzes the conversion of naturally occurring cellular P...

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Autors principals: Fevrier, Benoit, Vilette, Didier, Archer, Fabienne, Loew, Damarys, Faigle, Wolfgang, Vidal, Michel, Laude, Hubert, Raposo, Graça
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC470735/
https://ncbi.nlm.nih.gov/pubmed/15210972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308413101
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