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Small molecule modulators of pre-mRNA splicing in cancer therapy
Pre-mRNA splicing is a fundamental process in mammalian gene expression and alternative RNA splicing plays a considerable role in generating protein diversity. RNA splicing events are key to the pathology of numerous diseases, including cancers. Some tumors are molecularly addicted to specific RNA s...
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| Published in: | Trends Mol Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707101/ https://ncbi.nlm.nih.gov/pubmed/26700537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2015.11.005 |
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