AKT INHIBITION PROMOTES NON-AUTONOMOUS CANCER CELL SURVIVAL

Small-molecule inhibitors of AKT signaling are being evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibitor,...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Salony, Solé, Xavier, Alves, Cleidson P., Dey-Guha, Ipsita, Ritsma, Laila, Boukhali, Myriam, Lee, Ju H., Chowdhury, Joeeta, Ross, Kenneth N., Haas, Wilhelm, Vasudevan, Shobha, Ramaswamy, Sridhar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707053/
https://ncbi.nlm.nih.gov/pubmed/26637368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0414
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