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Integrin β1 activation induces an anti-melanoma host response

TGF-β is a cytokine thought to function as a tumor promoter in advanced malignancies. In this setting, TGF-β increases cancer cell proliferation, survival, and migration, and orchestrates complex, pro-tumorigenic changes in the tumor microenvironment. Here, we find that in melanoma, integrin β1-medi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ritsma, Laila, Dey-Guha, Ipsita, Talele, Nilesh, Sole, Xavier, Salony, Chowdhury, Joeeta, Ross, Kenneth N., Ramaswamy, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407755/
https://ncbi.nlm.nih.gov/pubmed/28448494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175300
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