AKT INHIBITION PROMOTES NON-AUTONOMOUS CANCER CELL SURVIVAL

Small-molecule inhibitors of AKT signaling are being evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibitor,...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Mol Cancer Ther
Главные авторы: Salony, Solé, Xavier, Alves, Cleidson P., Dey-Guha, Ipsita, Ritsma, Laila, Boukhali, Myriam, Lee, Ju H., Chowdhury, Joeeta, Ross, Kenneth N., Haas, Wilhelm, Vasudevan, Shobha, Ramaswamy, Sridhar
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707053/
https://ncbi.nlm.nih.gov/pubmed/26637368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0414
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы