Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles

The features of protective murine antibodies to the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) have been rigorously investigated; however, the characteristics of protective human antibodies to GXM have not been defined. We produced monoclonal antibodies (MAbs) from Xen...

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Main Authors: Maitta, Robert W., Datta, Kausik, Chang, Qing, Luo, Robin X., Witover, Bradley, Subramaniam, Krishanthi, Pirofski, Liise-anne
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC470673/
https://ncbi.nlm.nih.gov/pubmed/15271943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4810-4818.2004
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