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Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles

The features of protective murine antibodies to the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) have been rigorously investigated; however, the characteristics of protective human antibodies to GXM have not been defined. We produced monoclonal antibodies (MAbs) from Xen...

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Detalhes bibliográficos
Main Authors: Maitta, Robert W., Datta, Kausik, Chang, Qing, Luo, Robin X., Witover, Bradley, Subramaniam, Krishanthi, Pirofski, Liise-anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470673/
https://ncbi.nlm.nih.gov/pubmed/15271943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4810-4818.2004
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