Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles

The features of protective murine antibodies to the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) have been rigorously investigated; however, the characteristics of protective human antibodies to GXM have not been defined. We produced monoclonal antibodies (MAbs) from Xen...

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Hlavní autoři: Maitta, Robert W., Datta, Kausik, Chang, Qing, Luo, Robin X., Witover, Bradley, Subramaniam, Krishanthi, Pirofski, Liise-anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC470673/
https://ncbi.nlm.nih.gov/pubmed/15271943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4810-4818.2004
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