Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles

The features of protective murine antibodies to the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) have been rigorously investigated; however, the characteristics of protective human antibodies to GXM have not been defined. We produced monoclonal antibodies (MAbs) from Xen...

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Bibliographische Detailangaben
Hauptverfasser: Maitta, Robert W., Datta, Kausik, Chang, Qing, Luo, Robin X., Witover, Bradley, Subramaniam, Krishanthi, Pirofski, Liise-anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470673/
https://ncbi.nlm.nih.gov/pubmed/15271943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4810-4818.2004
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