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Immunogenicity and Efficacy of Cryptococcus neoformans Capsular Polysaccharide Glucuronoxylomannan Peptide Mimotope-Protein Conjugates in Human Immunoglobulin Transgenic Mice

Peptide mimotopes of capsular polysaccharides have been proposed as antigens for vaccines against encapsulated pathogens. In this study, we determined the antibody response to and efficacy of P13, a peptide mimetic of the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM), in...

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Bibliografische gegevens
Hoofdauteurs: Maitta, Robert W., Datta, Kausik, Lees, Andrew, Belouski, Shelley Sims, Pirofski, Liise-anne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC343982/
https://ncbi.nlm.nih.gov/pubmed/14688097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.196-208.2004
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