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Immunogenicity and Efficacy of Cryptococcus neoformans Capsular Polysaccharide Glucuronoxylomannan Peptide Mimotope-Protein Conjugates in Human Immunoglobulin Transgenic Mice

Peptide mimotopes of capsular polysaccharides have been proposed as antigens for vaccines against encapsulated pathogens. In this study, we determined the antibody response to and efficacy of P13, a peptide mimetic of the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM), in...

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Autors principals: Maitta, Robert W., Datta, Kausik, Lees, Andrew, Belouski, Shelley Sims, Pirofski, Liise-anne
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC343982/
https://ncbi.nlm.nih.gov/pubmed/14688097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.196-208.2004
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