Immunogenicity and Efficacy of Cryptococcus neoformans Capsular Polysaccharide Glucuronoxylomannan Peptide Mimotope-Protein Conjugates in Human Immunoglobulin Transgenic Mice

Peptide mimotopes of capsular polysaccharides have been proposed as antigens for vaccines against encapsulated pathogens. In this study, we determined the antibody response to and efficacy of P13, a peptide mimetic of the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM), in...

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Detalhes bibliográficos
Main Authors: Maitta, Robert W., Datta, Kausik, Lees, Andrew, Belouski, Shelley Sims, Pirofski, Liise-anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343982/
https://ncbi.nlm.nih.gov/pubmed/14688097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.196-208.2004
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