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Immunogenicity and Efficacy of Cryptococcus neoformans Capsular Polysaccharide Glucuronoxylomannan Peptide Mimotope-Protein Conjugates in Human Immunoglobulin Transgenic Mice

Peptide mimotopes of capsular polysaccharides have been proposed as antigens for vaccines against encapsulated pathogens. In this study, we determined the antibody response to and efficacy of P13, a peptide mimetic of the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM), in...

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Main Authors: Maitta, Robert W., Datta, Kausik, Lees, Andrew, Belouski, Shelley Sims, Pirofski, Liise-anne
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC343982/
https://ncbi.nlm.nih.gov/pubmed/14688097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.196-208.2004
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