Monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan enhance fluconazole efficacy.

Monoclonal antibody (MAb) 2H1, which binds to the capsular glucuronoxylomannan (GXM) of the fungus Cryptococcus neoformans, prolonged survival and decreased fungal burden in an experimental murine infection. Fluconazole (FLU) is a triazole antibiotic which is effective against C. neoformans. The eff...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Mukherjee, J, Feldmesser, M, Scharff, M D, Casadevall, A
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1398
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