In Vitro and In Vivo Stability a Cryptococcus neoformans Glucuronoxylomannan Epitope That Elicits Protective Antibodies

The monoclonal antibody (MAb) 2H1 defines an epitope in Cryptococcus neoformans capsular glucuronoxylomannan (GXM) that can elicit protective antibodies. In murine models of cryptococcosis, MAb 2H1 administration prolongs survival and reduces fungal burden but seldom clears the infection. The mechan...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Cleare, Wendy, Cherniak, Robert, Casadevall, Arturo
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1999
Fag:	Fungal and Parasitic Infections
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.3096-3107.1999
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