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In Vitro and In Vivo Stability a Cryptococcus neoformans Glucuronoxylomannan Epitope That Elicits Protective Antibodies
The monoclonal antibody (MAb) 2H1 defines an epitope in Cryptococcus neoformans capsular glucuronoxylomannan (GXM) that can elicit protective antibodies. In murine models of cryptococcosis, MAb 2H1 administration prolongs survival and reduces fungal burden but seldom clears the infection. The mechan...
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Päätekijät: | , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
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American Society for Microbiology
1999
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC96627/ https://ncbi.nlm.nih.gov/pubmed/10338526 |
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