In Vitro and In Vivo Stability a Cryptococcus neoformans Glucuronoxylomannan Epitope That Elicits Protective Antibodies

The monoclonal antibody (MAb) 2H1 defines an epitope in Cryptococcus neoformans capsular glucuronoxylomannan (GXM) that can elicit protective antibodies. In murine models of cryptococcosis, MAb 2H1 administration prolongs survival and reduces fungal burden but seldom clears the infection. The mechan...

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Опубликовано в::	Infect Immun
Главные авторы:	Cleare, Wendy, Cherniak, Robert, Casadevall, Arturo
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1999
Предметы:	Fungal and Parasitic Infections
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.3096-3107.1999
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