Immunogenicity and Efficacy of Cryptococcus neoformans Capsular Polysaccharide Glucuronoxylomannan Peptide Mimotope-Protein Conjugates in Human Immunoglobulin Transgenic Mice

Peptide mimotopes of capsular polysaccharides have been proposed as antigens for vaccines against encapsulated pathogens. In this study, we determined the antibody response to and efficacy of P13, a peptide mimetic of the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM), in...

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Pubblicato in:	Infect Immun
Autori principali:	Maitta, Robert W., Datta, Kausik, Lees, Andrew, Belouski, Shelley Sims, Pirofski, Liise-anne
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.1.196-208.2004
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