Selenoprotein S-dependent Selenoprotein K Binding to p97(VCP) Protein Is Essential for Endoplasmic Reticulum-associated Degradation

Cytosolic valosin-containing protein (p97(VCP)) is translocated to the ER membrane by binding to selenoprotein S (SelS), which is an ER membrane protein, during endoplasmic reticulum-associated degradation (ERAD). Selenoprotein K (SelK) is another known p97(VCP)-binding selenoprotein, and the expres...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Lee, Jea Hwang, Park, Ki Jun, Jang, Jun Ki, Jeon, Yeong Ha, Ko, Kwan Young, Kwon, Joon Hyun, Lee, Seung-Rock, Kim, Ick Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706009/
https://ncbi.nlm.nih.gov/pubmed/26504085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680215
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