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Comparing the Affinity of GTPase-binding Proteins using Competition Assays

In this protocol we demonstrate a method for comparing the competition between GTPase-binding proteins. Such an approach is important for determining the binding capabilities of GTPases for two reasons: The fact that all interactions involve the same face of the GTPases means that binding events mus...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Williamson, Rosalind C., Bass, Mark D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705812/
https://ncbi.nlm.nih.gov/pubmed/26484896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53254
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