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Comprehensive Characterization of (S)GTP-Binding Proteins by Orthogonal Quantitative (S)GTP-Affinity Profiling and (S)GTP/GTP Competition Assays
[Image: see text] Thiopurine drugs are widely used as antileukemic drugs and immunosuppressive agents, and 6-thioguanosine triphosphate ((S)GTP) is a major metabolite for these drugs. Recent studies have suggested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)G...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American
Chemical
Society
2014
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014148/ https://ncbi.nlm.nih.gov/pubmed/24689502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac500588q |
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