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A robust assay to measure DNA topology-dependent protein binding affinity
DNA structure and topology pervasively influence aspects of DNA metabolism including replication, transcription and segregation. However, the effects of DNA topology on DNA-protein interactions have not been systematically explored due to limitations of standard affinity assays. We developed a metho...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402506/ https://ncbi.nlm.nih.gov/pubmed/25552413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1381 |
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