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Single-molecule Measurements of DNA Topology and Topoisomerases
Topological properties of DNA influence its mechanical and biochemical interactions. Genomic DNA is maintained in a state of topological homeostasis by topoisomerases and is subjected to mechanical stress arising from replication and segregation. Despite their fundamental roles, the effects of topol...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885172/ https://ncbi.nlm.nih.gov/pubmed/20382732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.092437 |
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