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Single-molecule Measurements of DNA Topology and Topoisomerases

Topological properties of DNA influence its mechanical and biochemical interactions. Genomic DNA is maintained in a state of topological homeostasis by topoisomerases and is subjected to mechanical stress arising from replication and segregation. Despite their fundamental roles, the effects of topol...

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Detalhes bibliográficos
Autor principal: Neuman, Keir C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885172/
https://ncbi.nlm.nih.gov/pubmed/20382732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.092437
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