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Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci
Progenitor-B cells recombine their immunoglobulin (Ig) loci to create unique antigen receptors. Despite a common recombination machinery, the Ig heavy and Ig light chain loci rearrange in a stepwise manner. We studied pre-pro-B cells and Rag(−/−) progenitor-B cells to determine whether Ig locus cont...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705691/ https://ncbi.nlm.nih.gov/pubmed/26384565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv928 |
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