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Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Maintaining cellular redox balance is vital for cell survival and tissue homoeostasis because imbalanced production of reactive oxygen species (ROS) may lead to oxidative stress and cell death. The antioxidant enzyme glutathione peroxidase 4 (Gpx4) is a key regulator of oxidative stress–induced cell...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Canli, Özge, Alankuş, Yasemin B., Grootjans, Sasker, Vegi, Naidu, Hültner, Lothar, Hoppe, Philipp S., Schroeder, Timm, Vandenabeele, Peter, Bornkamm, Georg W., Greten, Florian R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705604/
https://ncbi.nlm.nih.gov/pubmed/26463424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-654194
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