Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Maintaining cellular redox balance is vital for cell survival and tissue homoeostasis because imbalanced production of reactive oxygen species (ROS) may lead to oxidative stress and cell death. The antioxidant enzyme glutathione peroxidase 4 (Gpx4) is a key regulator of oxidative stress–induced cell...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Canli, Özge, Alankuş, Yasemin B., Grootjans, Sasker, Vegi, Naidu, Hültner, Lothar, Hoppe, Philipp S., Schroeder, Timm, Vandenabeele, Peter, Bornkamm, Georg W., Greten, Florian R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2016
Onderwerpen:
Red Cells, Iron, and Erythropoiesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705604/
https://ncbi.nlm.nih.gov/pubmed/26463424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-654194
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